Knowledge Center

Learn about the types of early intervention for children with Down syndrome — physical therapy, speech and language therapy, and occupational therapy — and how each contributes to the child's growth and development.

Learn about the health conditions that may accompany Down syndrome — from heart defects to vision and hearing issues — and how to face them with confidence and early planning.

Learn about the two types of prenatal Down syndrome tests — screening and diagnostic — and the physical characteristics doctors look for when diagnosing the condition after birth.

A message of support for every family who has received a Down syndrome diagnosis — reminding you that you are not alone, and that your journey with your child is full of possibility.

A practical guide to the correct terminology when talking about Down syndrome — how to use respectful, person-first language.

Discover the truth behind the most common myths about Down syndrome — 7 cards that debunk misconceptions and replace them with verified scientific and human facts.

21 scientific and human facts about Down syndrome — from prevalence and causes to health, abilities, and rights.

Learn about prenatal screening tests for Down syndrome — including serum screening and ultrasound — as well as definitive diagnostic tests such as amniocentesis and chorionic villus sampling, plus how diagnosis is confirmed at birth.

Learn about the three types of Down syndrome: Trisomy 21 (95%), Translocation (4%), and Mosaic (1%), and discover the incidence rates by mother's age.

Explore the history of Down syndrome from John Langdon Down's description in 1866 to the identification of chromosome 21 in 1959, and learn what research reveals about its causes today.

Down syndrome is a chromosomal condition occurring in about one in 700 births. Learn about its genetic causes, physical characteristics, and how people with Down syndrome lead fulfilling lives.